Jarrow Formulas 5-HTP 50mg, Brain and Memory Support, 90 Caps

May 6, 2018 - Comment

View larger Product Profile 5-Hydroxytryptophan (5-HTP) is an amino acid naturally produced by the body from the essential amino acid L-tryptophan. 5-HTP is the immediate precursor to serotonin (5-hydroxytryptamine, 5-HT) and also a precursor to melatonin. In the brain, serotonin and melatonin help regulate sleep, mood, temperature, and appetite. As such, 5-HTP and L-tryptophan are

Buy Now! $10.93Amazon.com Price
(as of 6:38 am BST - Details)

View larger Product Profile

5-Hydroxytryptophan (5-HTP) is an amino acid naturally produced by the body from the essential amino acid L-tryptophan. 5-HTP is the immediate precursor to serotonin (5-hydroxytryptamine, 5-HT) and also a precursor to melatonin. In the brain, serotonin and melatonin help regulate sleep, mood, temperature, and appetite. As such, 5-HTP and L-tryptophan are often taken as supplements to these roles.* Yet even though L-tryptophan can be transformed into 5-HTP in the body, the two should not be considered interchangeable for use. The conversion of tryptophan to 5-HTP is the rate-limiting step in neurotransmitter production and, in addition, L-tryptophan is utilized for a variety of other purposes in the body leading to less serotonin support than may be assumed. In purified form, humans have been consuming 5-HTP for over forty years.

Distinguishing Features:

Sourced botanically from Griffonia simplicifoliaSerotonin & melatonin precursor View larger 5-HTP vs. L-Tryptophan

The body uses L-tryptophan for other metabolic purposes besides serotonin and melatonin production. For example, L-tryptophan is incorporated into proteins and also acts as a precursor in niacin biosynthesis. L-tryptophan absorption in the intestines requires a shared amino acid transporter, meaning that competition with other amino acids from dietary sources can lead to poor L-tryptophan absorption. A similar specific, active transport mechanism is required for L-tryptophan entry into the brain. A number of other physiological and biochemical parameters, such as stress, insulin response, and vitamin B6 levels can conspire to prevent L-tryptophan from becoming serotonin.

In contrast, 5-HTP is not incorporated into proteins and cannot be used to produce niacin. 5-HTP does not require an intestinal transporter for absorption and is absorbed well even in the presence of other amino acids from food, with about 70 percent of that ingested ending up in the bloodstream. Also, since 5-HTP participates in fewer biosynthetic pathways it is inherently less susceptible to metabolic diversion. The only hindrance of importance for ingested 5-HTP is the activity of peripheral decarboxylase enzymes, which can convert 5-HTP to serotonin before crossing the blood-brain barrier. However, the results observed in 5-HTP research demonstrate that this is not a major concern.

View larger Serotonin & The Second Brain

Some now use the phrase “our second brain” to refer to the impact our digestive tract can have on the entirety of the body. An example of this is the gut-brain axis, which involves extensive bidirectional signaling and feedback between gut and brain. For anyone who has attempted to diet in the past, this may already be understood experientially.

Serotonin plays a significant, yet not completely understood role in the human digestive tract and gut-brain axis. In fact, research demonstrates 5-HTP may even affect leptin, which helps to regulate intake and appetite.* Such a connection may help explain results in overweight individuals who were able to exert much better control over their diets when taking 5-HTP.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product Features

  • 5-Hydroxytryptophan Capsules
  • May Be Useful In Promoting Mental Health (as a precursor to serotonin)
  • Melatonin Precursor: May Promote Sleep

Comments

Jax says:

Miracle This product saved my life. If you’re debating whether or not to try it, I hope this will be the sign for you to just do it. I no longer have crying spells all day long for no reason. I can think straight. I actually laughed out loud… this is a MIRACLE. I started with 50mg at night, and felt a difference after only a few days. Then I started taking 100mg at night and felt even better. After about a month, I take 100mg in the morning, and I still take 100mg at night. It doesn’t make me too…

Christopher says:

I got to there because I was feeling so bad that I actually typed into Google Hey everyone, I’ve been using 5-HTP along with L-Tyrosine for six weeks. These products are a life changer for me! I read about this amino acid, (L-Tyrosine) in an article at psychologytoday.com. I got to there because I was feeling so bad that I actually typed into Google; ” How can I stop feeling so bad”, which, since the inception of the internet, I have done many times. It was actually a casual mention of L-Tyrosine. Then I came straight here to Amazon to see if I could get it and…

Kelly Rutter says:

during my worst times, I did not have access to psychiatric … I would be remiss not to write a review singing the praises of this supplement. I am currently 33 years old. What I did not realize for much of my life is that I had been clinically depressed since junior high. After college, I began to have periodic major depressive episodes. There is no mistaking those. If you have had one, you know what I mean. Anyway, during my worst times, I did not have access to psychiatric health care. I now recognize that as a blessing. Some thoughtless doctor would…

Write a comment

*